Natural 100%Pure Bulk Periwinkle Extract Vinca Minor Extract with High Quality
Product Description
Introduction:
Periwinkle extract is derived from Catharanthus roseus (formerly Vinca rosea), a flowering plant with a dual identity in both traditional medicine and modern pharmacology. This complex extract contains over 130 characterized alkaloids, most notably vinblastine and vincristine - two compounds that revolutionized cancer chemotherapy. The extract's phytochemical profile varies significantly between leaf, root, and flower sources, with leaf-derived extracts containing the highest concentration of bioactive vinca alkaloids. While the whole plant has been used in Ayurvedic medicine for diabetes management, modern applications focus on its cytotoxic alkaloids which interfere with microtubule formation in rapidly dividing cells. The extract's bitter taste and light-to-dark brown coloration reflect its complex mixture of indole and dihydroindole alkaloids, flavonoids, and phenolic compounds. Current research explores standardized extracts with optimized alkaloid ratios to balance efficacy and safety profiles.
Items |
Specification |
Extract Ratio |
/ |
Extract Solvent |
Water |
Mesh size |
NLT 90% through 80 |
Moisture Content |
≤5% |
Ash Content |
≤5% |
Heavy metals |
≤10ppm |
As |
≤1ppm |
Cd |
≤1ppm |
Pb |
≤3ppm |
Total Plate Count |
≤1,000cfu/g |
Total Yeast & Mold |
≤100cfu/g |
Applications of Periwinkle Extract
Periwinkle extract serves critical roles in both pharmaceutical and nutraceutical applications. In oncology, isolated vinca alkaloids form the basis of chemotherapeutic regimens for lymphomas, leukemias, and solid tumors, with vinblastine particularly effective against Hodgkin's disease and vincristine essential for pediatric ALL protocols. The extract's hypoglycemic properties, attributed to alkaloids like leurosine, support its use in diabetic supplements targeting glucose metabolism. Neurological applications are emerging for vincamine-rich extracts, which demonstrate cerebrovascular dilating effects potentially beneficial for cognitive function and age-related memory decline. The extract's antimicrobial activity against drug-resistant pathogens has spurred research into topical formulations for wound care. In controlled doses, specific alkaloid fractions show promise for autoimmune condition management through immunomodulatory mechanisms. Recent advances in plant tissue culture allow for sustainable production of target alkaloids without wild harvesting. Quality standardization is particularly crucial, with HPLC analysis required to verify alkaloid concentrations and ratios - typically 0.2-1% total vinca alkaloids for therapeutic extracts. Emerging biotechnological approaches focus on elicitation techniques to enhance production of specific alkaloids while reducing unwanted compounds. The extract's multifaceted bioactivity continues to inspire research into novel applications, including anti-angiogenic therapies and microtubule-stabilizing approaches for neurodegenerative diseases.
Company Profile
Changsha Vigorous-tech Co., Ltd. is a manufacturer and supplier of Botanical Extracts, located in Changsha, Hunan. We have two natural extract laboratories, one analysis and test center, a pilot production base, two factories, can finish from small to large various stages of development, and we have can make the scientific research strength of standard control product quality, and enhance the competitiveness of their products. We have advanced equipment and analysis the extraction and separation of the testing instrument, including multifunction extractor, microwave extraction device, membrane separation device, the highly effective liquid phase color spectrometer, imported high half preparation color spectrometer, gas phase color spectrometer, infrared spectrometer, uv-vis spectrophotometer etc.
Manufacturing process of Periwinkle Extract
Certifications
The following certificates available if you require:
ISO / ISO22000
COA / MSDS
Gluten Free / Allergen Free
GMO Free / Non Irradiation
Organic certificate/ Certificate of origin(Form/CO)/Kosher/Halal/CGMP
Phytosanitary certificate / Microbial certificate
Food certificate / Heavy metal statement
Residual solvent meet E.P. requirements. / Non-Animal Material

Packaging & Shipping
Our Storage and Packaging(Very tidy,No dusty):
How about sample policy?
If we have the sample in stock.we will provide free sample to you.If we don't have it in stock. then you should pay the sample fee.any way,the sample fee will pay back to you when you confirm the roder.
Packing Detail: Packed in paper-drums and two plastic-bags inside. Net Weight: 25kgs/drum.
Storage Situation:Stored in a cool and dry well-closed container, keep away from moisture and strong light / heat.
Shelf Life: two years under well Storage situation and stored away from direct sun light.

Express(Send Free sample):
Which shipping way is available and how to track?
By sea to your nearest port
By air to your nearest airport
By express (DHL,UPS,FEDEX,TNT,EMS)to your door
When ur order shipping out . we will provide u a tracking no. then u can know clearly the status of the goods

Our Advantages
Pre-sales
1.High quality control
2.Free samples(5-20g)
3.Kosher, MSDS, Food certification, etc
Sales
1.Professional sales director
2.Excellent R&D back up
3.24 hours service
After-sales
1.Shipment tracking
2.Goods quality following
3.Periodically contacting

FAQ
Q:What about your standard delivery time?
A:Normally the delivery time is 3-15 days. If you need it in a hurry, we will make immediate delivery.
Q:Is there any discount?
A:Sure, Prices are closely related to the quantity. The more, the cheaper.
Q:Can you provide samples?
A:Yes, normally we can provide samples 5-20 g. You could purchase a small amount of product too.If you need it, please don't hesitate to contact us.
Q:Do you have guarantee on your products?
A:The product are 100% pure natural with high quality. We are sure that every batch comes with the unique COA. All extracts are tested in-house; random extracts are tested by authoritative analytical labs.
Q: What is your MOQ?
A: Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q: What's your payment terms?
A: You can pay to us via T/T Bank, Visa Card, Master Card, e-Checking, Paypal, Western Union.
Q:How to ship and delivery?
A:Transit could be DHL,UPS,TNT, FEDEX, EMS. For mass orders, it will be delivered by air or sea.
Exhibition
https://vigorous-tech.en.made-in-china.com/contact-info.html